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glnE protein (Acinetobacter baumannii) - STRING interaction network
"glnE" - Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme in Acinetobacter baumannii
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnEBifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (916 aa)    
Predicted Functional Partners:
AIL77605.1
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (887 aa)
 
   
  0.864
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (308 aa)
              0.820
glnA
Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (469 aa)
 
     
  0.763
glnB
Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method- Protein Homology (112 aa)
 
 
  0.729
AIL79213.1
Signal transduction histidine kinase; Derived by automated computational analysis using gene prediction method- Protein Homology (422 aa)
   
        0.645
AIL78834.1
Peroxiredoxin; Derived by automated computational analysis using gene prediction method- Protein Homology (153 aa)
            0.642
fis
Bacterial regulatory, Fis family protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the transcriptional regulatory Fis family (89 aa)
   
          0.600
AIL79210.1
Nucleoside-diphosphate sugar epimerase; Derived by automated computational analysis using gene prediction method- Protein Homology (296 aa)
              0.587
gtrOC3
Lipopolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology (255 aa)
              0.559
gtrOC2
Glycosyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (342 aa)
              0.557
Your Current Organism:
Acinetobacter baumannii
NCBI taxonomy Id: 470
Other names: A. baumannii, ATCC 19606, Acinetobacter baumannii, Acinetobacter genomosp. 2, Acinetobacter genomospecies 2, Bacterium anitratum, CCUG 19096, CIP 70.34, DSM 30007, JCM 6841, NCCB 85021, NCTC 12156
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