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purL protein (Geobacillus sp. WCH70) - STRING interaction network
"purL" - Phosphoribosylformylglycinamidine synthase subunit PurL in Geobacillus sp. WCH70
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Predicted Interactions
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textmining
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purLPhosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (742 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (228 aa)
  0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (194 aa)
 
  0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG- gka-GK0265 phosphoribosylaminoimidazole synthetase; TIGRFAM- phosphoribosylformylglycinamidine cyclo-ligase; PFAM- AIR synthase related protein domain protein; AIR synthase related protein (346 aa)
 
  0.999
purS
Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (84 aa)
 
 
  0.998
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (470 aa)
 
 
  0.998
purD
TIGRFAM- phosphoribosylamine/glycine ligase; PFAM- phosphoribosylglycinamide synthetase; KEGG- gka-GK0268 phosphoribosylamine--glycine ligase; Belongs to the GARS family (430 aa)
 
  0.996
purC
KEGG- gka-GK0260 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM- phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM- SAICAR synthetase (242 aa)
 
 
  0.995
purH
Bifunctional purine biosynthesis protein PurH; KEGG- gka-GK0267 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART- AICARFT/IMPCHase bienzyme formylation region (512 aa)
 
 
  0.995
ACS23184.1
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- afl-Aflv_0230 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (431 aa)
 
 
  0.969
purK
N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) (384 aa)
 
   
  0.968
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70, Geobacillus sp. WCH70
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