STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recXRegulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. (271 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
  
 0.852
ACS23369.1
PFAM: Protein of unknown function DUF1811; KEGG: gka:GK0453 hypothetical protein.
  
    0.810
ACS24048.1
PFAM: RecA domain protein; KEGG: gka:GK1295 hypothetical protein.
  
 
 0.808
ACS24050.1
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.808
ACS25207.1
TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: gtn:GTNG_2511 single-strand DNA-specific exonuclease.
 
   
 0.608
cinA
TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis domain protein; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: gka:GK1294 competence damage-inducible protein A.
 
   
 0.606
ACS25145.1
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: gtn:GTNG_2451 DNA internalization-related competence protein ComEC.
 
   
 0.597
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
  
 0.591
ACS25020.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.568
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.528
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70
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