STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS23499.1Metal-dependent hydrolase; Possible metal-dependent hydrolase; Belongs to the metal hydrolase YfiT family. (176 aa)    
Predicted Functional Partners:
ACS24370.1
PFAM: protein of unknown function DUF1094; KEGG: gtn:GTNG_1676 hypothetical protein; Belongs to the UPF0403 family.
  
     0.699
ACS25000.1
PFAM: protein of unknown function DUF1094; KEGG: gtn:GTNG_2297 hypothetical protein; Belongs to the UPF0403 family.
  
     0.691
ACS24891.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: afl:Aflv_1069 thioredoxin reductase.
  
     0.625
nuoI
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.576
ACS24534.1
PFAM: GCN5-related N-acetyltransferase; KEGG: bld:BLi00739 YjcK.
  
    0.520
bshC
Conserved hypothetical protein; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
  
   
 0.513
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.510
ACS23500.1
PFAM: major facilitator superfamily MFS_1; KEGG: gka:GK0617 antibiotic resistance protein (antibiotic efflux protein).
       0.499
ACS25301.1
TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; PFAM: fumarate reductase respiratory complex transmembrane subunit; KEGG: gka:GK2673 succinate dehydrogenase (cytochrome b558 subunit).
   
    0.499
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
    0.486
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.