STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnK5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (400 aa)    
Predicted Functional Partners:
mtnA
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
 
 0.999
ACS23725.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: gka:GK0948 ribose ABC transporter (substrate-binding protein).
 
    0.942
mtnN
Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.935
mtnB
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
 
  
 0.920
ACS23723.1
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: gtn:GTNG_0834 methylthioribose transport system permease protein.
 
   
 0.906
mtnD
Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
 
  
 0.904
mtnW
2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily.
 
  
 0.896
mtnX
2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene).
 
  
 0.843
ACS23724.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gtn:GTNG_0835 ABC-type sugar (aldose) transport system, ATPase component.
 
  
 0.806
ACS23599.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: gka:GK0717 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
   
  
 0.772
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70
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