node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS23608.1 | ACS24946.1 | GWCH70_0719 | GWCH70_2238 | TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: gtn:GTNG_0634 hydrolase HAD superfamily. | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | 0.914 |
ACS23608.1 | ACS24947.1 | GWCH70_0719 | GWCH70_2239 | TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: gtn:GTNG_0634 hydrolase HAD superfamily. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.924 |
ACS23608.1 | ribH | GWCH70_0719 | GWCH70_2236 | TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: gtn:GTNG_0634 hydrolase HAD superfamily. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.916 |
ACS23924.1 | ACS24019.1 | GWCH70_1064 | GWCH70_1159 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.407 |
ACS23924.1 | ACS24947.1 | GWCH70_1064 | GWCH70_2239 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.713 |
ACS23924.1 | guaB | GWCH70_1064 | GWCH70_0009 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.472 |
ACS23924.1 | ribBA | GWCH70_1064 | GWCH70_2237 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.734 |
ACS23924.1 | ribH | GWCH70_1064 | GWCH70_2236 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.821 |
ACS24019.1 | ACS23924.1 | GWCH70_1159 | GWCH70_1064 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.407 |
ACS24019.1 | ACS24946.1 | GWCH70_1159 | GWCH70_2238 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | 0.935 |
ACS24019.1 | ACS24947.1 | GWCH70_1159 | GWCH70_2239 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.691 |
ACS24019.1 | guaB | GWCH70_1159 | GWCH70_0009 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.571 |
ACS24019.1 | ribBA | GWCH70_1159 | GWCH70_2237 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.570 |
ACS24019.1 | ribH | GWCH70_1159 | GWCH70_2236 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.916 |
ACS24946.1 | ACS23608.1 | GWCH70_2238 | GWCH70_0719 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: gtn:GTNG_0634 hydrolase HAD superfamily. | 0.914 |
ACS24946.1 | ACS24019.1 | GWCH70_2238 | GWCH70_1159 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: gtn:GTNG_1121 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.935 |
ACS24946.1 | ACS24947.1 | GWCH70_2238 | GWCH70_2239 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ACS24946.1 | metK | GWCH70_2238 | GWCH70_2777 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.403 |
ACS24946.1 | ribBA | GWCH70_2238 | GWCH70_2237 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
ACS24946.1 | ribH | GWCH70_2238 | GWCH70_2236 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: gtn:GTNG_2224 riboflavin synthase subunit alpha. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.999 |