node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS24879.1 | cmk | GWCH70_2169 | GWCH70_2171 | PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: gtn:GTNG_2161 30S ribosomal protein S1. | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.961 |
ACS24879.1 | fni | GWCH70_2169 | GWCH70_2168 | PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: gtn:GTNG_2161 30S ribosomal protein S1. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.811 |
ACS24879.1 | ispE | GWCH70_2169 | GWCH70_0041 | PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: gtn:GTNG_2161 30S ribosomal protein S1. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.420 |
ACS24879.1 | ispH | GWCH70_2169 | GWCH70_2409 | PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: gtn:GTNG_2161 30S ribosomal protein S1. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.917 |
ACS25024.1 | cmk | GWCH70_2320 | GWCH70_2171 | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.486 |
ACS25024.1 | dxs | GWCH70_2320 | GWCH70_2319 | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.707 |
ACS25024.1 | fni | GWCH70_2320 | GWCH70_2168 | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.928 |
ACS25024.1 | ispE | GWCH70_2320 | GWCH70_0041 | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.404 |
ACS25024.1 | ispH | GWCH70_2320 | GWCH70_2409 | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.923 |
cmk | ACS24879.1 | GWCH70_2171 | GWCH70_2169 | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: gtn:GTNG_2161 30S ribosomal protein S1. | 0.961 |
cmk | ACS25024.1 | GWCH70_2171 | GWCH70_2320 | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | 0.486 |
cmk | fni | GWCH70_2171 | GWCH70_2168 | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.587 |
cmk | ispH | GWCH70_2171 | GWCH70_2409 | KEGG: gka:GK2227 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.800 |
dxr | dxs | GWCH70_1147 | GWCH70_2319 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.987 |
dxr | ispD | GWCH70_1147 | GWCH70_0086 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.984 |
dxr | ispE | GWCH70_1147 | GWCH70_0041 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.771 |
dxr | ispF | GWCH70_1147 | GWCH70_0087 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.850 |
dxr | ispG | GWCH70_1147 | GWCH70_2398 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.849 |
dxr | ispH | GWCH70_1147 | GWCH70_2409 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.830 |
dxs | ACS25024.1 | GWCH70_2319 | GWCH70_2320 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | PFAM: Polyprenyl synthetase; KEGG: gka:GK2393 geranyltranstransferase (farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family. | 0.707 |