STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (372 aa)    
Predicted Functional Partners:
ACS25139.1
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: gka:GK2510 stage II sporulation protein P (septal wall dissolution protein).
 
    0.914
ACS24954.1
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: gtn:GTNG_2235 stage V sporulation protein AD.
  
  
 0.877
ACS23675.1
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: gka:GK0854 stage V sporulation protein AD.
  
  
 0.875
ACS23674.1
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: gka:GK0853 stage V sporulation protein AC.
  
  
 0.838
ACS24955.1
PFAM: SpoVA protein; KEGG: gtn:GTNG_2236 stage V sporulation protein AC-like protein.
  
  
 0.836
ACS25019.1
KEGG: gtn:GTNG_2318 stage IV sporulation protein B; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
  
    0.822
ACS24865.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.803
ACS22993.1
TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: gtn:GTNG_0049 stage V sporulation protein T.
  
  
 0.781
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.781
ACS24951.1
PFAM: GerA spore germination protein; KEGG: gka:GK2301 stage V sporulation protein AF.
  
    0.778
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70
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