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hisS protein (Geobacillus sp. WCH70) - STRING interaction network
"hisS" - Histidine--tRNA ligase in Geobacillus sp. WCH70
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
hisSHistidine--tRNA ligase; KEGG- afl-Aflv_0730 histidyl-tRNA synthetase; TIGRFAM- histidyl-tRNA synthetase; PFAM- tRNA synthetase class II (G H P and S); Anticodon-binding domain protein (423 aa)    
Predicted Functional Partners:
aspS
Aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps- L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily (594 aa)
 
   
  0.976
pheT
KEGG- afl-Aflv_0543 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (804 aa)
 
   
  0.925
lysS
Lysine--tRNA ligase; KEGG- gka-GK0074 lysyl-tRNA synthetase; TIGRFAM- lysyl-tRNA synthetase; PFAM- tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family (494 aa)
     
 
  0.924
pheS
TIGRFAM- phenylalanyl-tRNA synthetase, alpha subunit; PFAM- phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG- afl-Aflv_0542 phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily (344 aa)
 
 
  0.876
thrS
Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) (644 aa)
 
 
  0.860
serS
Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (424 aa)
 
 
  0.855
secD
Multifunctional fusion protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily (750 aa)
   
   
  0.850
tyrS
Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily (419 aa)
   
   
  0.847
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (880 aa)
 
   
  0.843
leuS
Leucine--tRNA ligase; TIGRFAM- leucyl-tRNA synthetase; KEGG- afl-Aflv_0425 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (805 aa)
   
   
  0.823
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70, Geobacillus sp. WCH70
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