node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS23327.1 | ACS24329.1 | GWCH70_0407 | GWCH70_1526 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | 0.930 |
ACS23327.1 | ACS24360.1 | GWCH70_0407 | GWCH70_1562 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | 0.902 |
ACS23327.1 | ACS25273.1 | GWCH70_0407 | GWCH70_2578 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gtn:GTNG_2572 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.779 |
ACS23327.1 | ACS25274.1 | GWCH70_0407 | GWCH70_2579 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.995 |
ACS23327.1 | hemA | GWCH70_0407 | GWCH70_2582 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.665 |
ACS23327.1 | hemC | GWCH70_0407 | GWCH70_2580 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.974 |
ACS23327.1 | hemE | GWCH70_0407 | GWCH70_0649 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.921 |
ACS24329.1 | ACS23327.1 | GWCH70_1526 | GWCH70_0407 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.930 |
ACS24329.1 | ACS24360.1 | GWCH70_1526 | GWCH70_1562 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | 0.931 |
ACS24329.1 | ACS25273.1 | GWCH70_1526 | GWCH70_2578 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gtn:GTNG_2572 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.760 |
ACS24329.1 | ACS25274.1 | GWCH70_1526 | GWCH70_2579 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.909 |
ACS24329.1 | ACS25276.1 | GWCH70_1526 | GWCH70_2581 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | PFAM: cytochrome c assembly protein; KEGG: gka:GK2646 negative effector of the concentration of HemA. | 0.504 |
ACS24329.1 | hemA | GWCH70_1526 | GWCH70_2582 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.432 |
ACS24329.1 | hemC | GWCH70_1526 | GWCH70_2580 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.978 |
ACS24329.1 | hemE | GWCH70_1526 | GWCH70_0649 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.924 |
ACS24360.1 | ACS23327.1 | GWCH70_1562 | GWCH70_0407 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_0385 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.902 |
ACS24360.1 | ACS24329.1 | GWCH70_1562 | GWCH70_1526 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gka:GK1829 uroporphyrinogen-III synthase. | 0.931 |
ACS24360.1 | ACS25273.1 | GWCH70_1562 | GWCH70_2578 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gtn:GTNG_2572 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.789 |
ACS24360.1 | ACS25274.1 | GWCH70_1562 | GWCH70_2579 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.995 |
ACS24360.1 | hemA | GWCH70_1562 | GWCH70_2582 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gtn:GTNG_1682 uroporphyrin-III C-methyltransferase-like protein; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.682 |