STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1241Acetyl-CoA hydrolase-like protein; KEGG: scl:sce3293 4-hydroxybutyrate coenzyme A transferase. (429 aa)    
Predicted Functional Partners:
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.856
Tcur_1964
Citrate synthase I; KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase.
  
 
 0.818
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
  
 0.793
Tcur_2505
KEGG: met:M446_3042 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein.
  
  
 0.657
Tcur_2506
PFAM: methylmalonyl-CoA mutase; KEGG: bbt:BBta_3023 methylmalonyl-CoA mutase small subunit (MCM-beta).
  
  
 0.657
Tcur_2347
PFAM: cobalamin B12-binding domain protein; KEGG: rfr:Rfer_3887 cobalamin B12-binding.
 
  
 0.528
Tcur_2093
PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; KEGG: net:Neut_1995 phosphate acetyltransferase.
  
  
 0.509
Tcur_3675
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: gsu:GSU2449 alpha-ketoglutarate decarboxylase.
   
 
 0.505
Tcur_0834
PFAM: Citrate synthase; KEGG: pzu:PHZ_c0162 citrate synthase GltA; Belongs to the citrate synthase family.
  
 
 0.485
Tcur_4061
Mannose-6-phosphate isomerase; KEGG: smd:Smed_4018 RpiR family transcriptional regulator.
 
  
 0.478
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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