STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2276PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sml:Smlt0130 putative modulator of DNA gyrase. (503 aa)    
Predicted Functional Partners:
Tcur_2275
Zn-dependent protease and their inactivated protein-like protein; KEGG: ccs:CCNA_02915 microcin-processing peptidase 1 (PmbA).
 
     0.955
Tcur_4180
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: rsq:Rsph17025_1847 dihydrolipoamide dehydrogenase.
      
 0.744
Tcur_1314
KEGG: cvi:CV_1564 precorrin-4 C11-methyltransferase protein; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
      
 0.740
Tcur_2278
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_6034 enoyl-(acyl carrier protein) reductase.
     
 0.649
Tcur_2277
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.525
Tcur_2239
Hypothetical protein.
  
     0.509
Tcur_0052
PFAM: protein of unknown function DUF323; KEGG: scl:sce5487 protein kinase.
     
 0.466
egtB
Protein of unknown function DUF323; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
     
 0.466
Tcur_2283
PFAM: Phosphoglycerate mutase; KEGG: met:M446_2115 phosphoglycerate mutase.
      
 0.452
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
      
 0.452
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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