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prcB1 protein (Thermomonospora curvata) - STRING interaction network
"prcB1" - Proteasome subunit beta 1 in Thermomonospora curvata
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prcB1Proteasome subunit beta 1; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation; Belongs to the peptidase T1B family (284 aa)    
Predicted Functional Partners:
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation; Belongs to the peptidase T1A family (228 aa)
 
  0.989
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis (587 aa)
 
 
  0.927
Tcur_0127
annotation not available (187 aa)
   
 
 
  0.868
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (452 aa)
 
   
  0.839
prcB2
Proteasome subunit beta 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation; Belongs to the peptidase T1B family (280 aa)
   
   
 
0.806
pup
Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (69 aa)
 
   
  0.795
Tcur_2308
PFAM- protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein (505 aa)
 
     
  0.717
Tcur_2310
KEGG- hypothetical protein (506 aa)
   
 
  0.675
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family (505 aa)
     
 
  0.601
Tcur_3873
PFAM- Mov34/MPN/PAD-1 family protein; SMART- Mov34/MPN/PAD-1 family protein; KEGG- nmu-Nmul_A0971 Mov34/MPN/PAD-1 (137 aa)
     
 
  0.600
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata, Thermomonospora curvata DSM 43183, Thermomonospora curvata DSM43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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