STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2469Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator. (229 aa)    
Predicted Functional Partners:
Tcur_2468
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 
 0.956
Tcur_0111
Histidine kinase; KEGG: scl:sce5432 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 0.836
Tcur_2846
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 0.834
Tcur_2303
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 0.831
Tcur_4492
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 0.826
Tcur_1533
Histidine kinase; KEGG: lch:Lcho_0902 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein.
 
 0.824
Tcur_1652
Histidine kinase; KEGG: pol:Bpro_4297 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein.
 
 0.824
Tcur_1301
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 
 0.817
Tcur_0153
Histidine kinase; KEGG: reh:H16_A0780 signal transduction histidine kinase containing PAS/PAC sensor domain; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein.
 
 0.810
Tcur_3280
Histidine kinase; KEGG: reh:H16_A1985 signal transduction histidine kinase containing PAS/PAC sensor domain; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.799
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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