STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_3449PFAM: Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; globin; KEGG: hypothetical protein; K05916 nitric oxide dioxygenase; Belongs to the globin family. (399 aa)    
Predicted Functional Partners:
Tcur_3450
PFAM: protein of unknown function UPF0074; KEGG: reu:Reut_A3220 BadM/Rrf2 family transcriptional regulator.
   
 0.973
Tcur_4102
PFAM: Activator of Hsp90 ATPase 1 family protein.
  
  
 0.891
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.796
Tcur_2412
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: bam:Bamb_3936 nitrite reductase (NAD(P)H), large subunit.
  
  
 0.612
Tcur_2413
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: scl:sce3488 nitrite reductase.
  
  
 0.612
Tcur_0195
PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: pmy:Pmen_1573 MOSC domain-containing protein.
      0.559
Tcur_4775
Multi-sensor signal transduction histidine kinase; KEGG: bbt:BBta_6262 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein.
  
  
 0.555
Tcur_3555
KEGG: dvm:DvMF_2963 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein.
  
  
 0.553
Tcur_2644
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; KEGG: mxa:MXAN_6735 sensor histidine kinase/response regulator.
  
  
 0.518
Tcur_2466
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; globin; Oxidoreductase FAD-binding domain protein; KEGG: pna:Pnap_4185 oxidoreductase FAD/NAD(P)- binding subunit; Belongs to the globin family.
 
  
0.494
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
Server load: low (24%) [HD]