STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_3555KEGG: dvm:DvMF_2963 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein. (943 aa)    
Predicted Functional Partners:
Tcur_4775
Multi-sensor signal transduction histidine kinase; KEGG: bbt:BBta_6262 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.999
Tcur_2644
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; KEGG: mxa:MXAN_6735 sensor histidine kinase/response regulator.
 
 
 0.996
Tcur_2645
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6734 response regulator/sensory box histidine kinase.
 
 0.984
Tcur_1606
Putative PAS/PAC sensor protein; KEGG: met:M446_3558 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein.
 
 0.976
Tcur_0838
Putative PAS/PAC sensor protein; KEGG: gme:Gmet_1230 serine phosphatase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein.
 
 
 0.975
Tcur_4776
Multi-sensor hybrid histidine kinase; KEGG: reu:Reut_B4539 response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.974
Tcur_3716
Putative integral membrane sensor protein; PFAM: MHYT domain protein; KEGG: mrd:Mrad2831_2786 multi-sensor signal transduction histidine kinase.
   
 0.957
Tcur_3562
Diguanylate cyclase/phosphodiesterase; KEGG: azo:azo0565 GGDEF/EAL/PAS/PAC/GAF-domain- containing protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.950
Tcur_2814
Putative PAS/PAC sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein; KEGG: gme:Gmet_2062 serine phosphatase.
  
 
 0.908
Tcur_3705
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: gsu:GSU1007 GAF domain/HD domain-containing protein.
 
 0.876
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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