STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nhal_1912PFAM: Aldehyde Dehydrogenase; KEGG: dat:HRM2_11640 NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (463 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.939
Nhal_2077
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: noc:Noc_1733 multifunctional fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.934
Nhal_2479
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: noc:Noc_0826 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.934
Nhal_1873
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_2077 6-phosphogluconate dehydrogenase, NAD-binding.
  
 
 0.926
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.926
Nhal_1075
PFAM: acylphosphatase; KEGG: noc:Noc_0888 acylphosphatase.
    
 0.909
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
    
 0.907
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.901
Nhal_2762
KEGG: noc:Noc_0494 kinase-like.
     
  0.900
Nhal_1437
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
0.890
Your Current Organism:
Nitrosococcus halophilus
NCBI taxonomy Id: 472759
Other names: N. halophilus Nc 4, Nitrosococcus halophilus Nc 4, Nitrosococcus halophilus str. Nc 4, Nitrosococcus halophilus strain Nc 4
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