node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Daud_2218 | guaA | Daud_2218 | Daud_1635 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.826 |
Daud_2218 | ispH | Daud_2218 | Daud_1178 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.417 |
Daud_2218 | pheT | Daud_2218 | Daud_1377 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | KEGG: mta:Moth_1750 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.871 |
Daud_2218 | prs | Daud_2218 | Daud_0069 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.577 |
Daud_2218 | pth | Daud_2218 | Daud_0071 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.877 |
glmU | mfd | Daud_0068 | Daud_0072 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.496 |
glmU | prs | Daud_0068 | Daud_0069 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.994 |
glmU | pth | Daud_0068 | Daud_0071 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.652 |
glmU | rplY | Daud_0068 | Daud_0070 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.652 |
guaA | Daud_2218 | Daud_1635 | Daud_2218 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | 0.826 |
guaA | ispH | Daud_1635 | Daud_1178 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.763 |
guaA | pheT | Daud_1635 | Daud_1377 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: mta:Moth_1750 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.926 |
guaA | prs | Daud_1635 | Daud_0069 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.849 |
guaA | pth | Daud_1635 | Daud_0071 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.745 |
guaA | rplY | Daud_1635 | Daud_0070 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.575 |
guaA | tilS | Daud_1635 | Daud_0086 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.447 |
guaA | trpF | Daud_1635 | Daud_1187 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: dps:DP1623 related to N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.442 |
ispH | Daud_2218 | Daud_1178 | Daud_2218 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: chy:CHY_0031 GTP-binding protein YchF. | 0.417 |
ispH | guaA | Daud_1178 | Daud_1635 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.763 |
ispH | mfd | Daud_1178 | Daud_0072 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.479 |