STRINGSTRING
PITG_01201 protein (Phytophthora infestans) - STRING interaction network
"PITG_01201" - ATP-dependent DNA helicase, putative in Phytophthora infestans
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITG_01201ATP-dependent DNA helicase, putative (548 aa)    
Predicted Functional Partners:
PITG_02495
Phosphatidylinositol kinase (PIK-L4) (3049 aa)
     
  0.956
PITG_18634
DNA topoisomerase, putative; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (907 aa)
   
  0.906
PITG_01300
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1329 aa)
   
  0.886
PITG_07823
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (807 aa)
   
  0.883
PITG_05679
Replication protein A 70 kDa DNA-binding subunit, putative (629 aa)
     
  0.882
PITG_07874
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1505 aa)
   
  0.876
PITG_03624
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (389 aa)
   
  0.874
PITG_16978
Crossover junction endonuclease MUS81-like protein (572 aa)
     
  0.861
PITG_12104
ATP-dependent DNA helicase 2 subunit, putative (607 aa)
     
  0.860
PITG_21279
Putative uncharacterized protein (129 aa)
   
  0.859
Your Current Organism:
Phytophthora infestans
NCBI taxonomy Id: 4787
Other names: P. infestans, Phytophthora infestans, potato late blight, potato late blight agent, potato late blight fungus
Server load: low (8%) [HD]