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PITG_03624 protein (Phytophthora infestans) - STRING interaction network
"PITG_03624" - Flap endonuclease 1 in Phytophthora infestans
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PITG_03624Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (389 aa)    
Predicted Functional Partners:
PITG_14397
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (259 aa)
     
  0.993
PITG_02805
DNA mismatch repair protein Msh2, putative (816 aa)
   
  0.964
PITG_13158
Double-strand break repair protein, putative (863 aa)
   
  0.940
PITG_13336
DNA2-like helicase (1500 aa)
   
  0.919
PITG_03389
Replication factor C subunit 4 (339 aa)
   
  0.904
PITG_19314
Replication factor C subunit 3 (352 aa)
   
  0.886
PITG_04614
DNA ligase, putative (497 aa)
 
  0.885
PITG_04709
DNA ligase (3896 aa)
   
  0.884
PITG_16527
Bloom syndrome protein, DEAD/DEAH box helicase (400 aa)
   
  0.874
PITG_14828
ATP-dependent DNA helicase, putative (653 aa)
   
  0.874
Your Current Organism:
Phytophthora infestans
NCBI taxonomy Id: 4787
Other names: P. infestans, Phytophthora infestans, potato late blight, potato late blight agent, potato late blight fungus
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