node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Namu_1766 | Namu_1877 | Namu_1766 | Namu_1877 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.951 |
Namu_1766 | Namu_2341 | Namu_1766 | Namu_2341 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: Lactate/malate dehydrogenase; KEGG: mpt:Mpe_B0497 malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. | 0.591 |
Namu_1766 | Namu_2357 | Namu_1766 | Namu_2357 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; KEGG: mpt:Mpe_B0560 pyruvate phosphate dikinase. | 0.906 |
Namu_1766 | Namu_3070 | Namu_1766 | Namu_3070 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | KEGG: ank:AnaeK_4367 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.900 |
Namu_1766 | Namu_4080 | Namu_1766 | Namu_4080 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; KEGG: ppd:Ppro_0642 pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. | 0.906 |
Namu_1766 | eno | Namu_1766 | Namu_4431 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.988 |
Namu_1766 | mdh | Namu_1766 | Namu_2256 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.620 |
Namu_1766 | pckG | Namu_1766 | Namu_5314 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.936 |
Namu_1766 | ppc | Namu_1766 | Namu_4447 | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.936 |
Namu_1877 | Namu_1766 | Namu_1877 | Namu_1766 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.951 |
Namu_1877 | Namu_2341 | Namu_1877 | Namu_2341 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: Lactate/malate dehydrogenase; KEGG: mpt:Mpe_B0497 malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. | 0.932 |
Namu_1877 | Namu_2357 | Namu_1877 | Namu_2357 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; KEGG: mpt:Mpe_B0560 pyruvate phosphate dikinase. | 0.913 |
Namu_1877 | Namu_3070 | Namu_1877 | Namu_3070 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | KEGG: ank:AnaeK_4367 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.951 |
Namu_1877 | Namu_4080 | Namu_1877 | Namu_4080 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; KEGG: ppd:Ppro_0642 pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. | 0.913 |
Namu_1877 | Namu_4703 | Namu_1877 | Namu_4703 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Citrate synthase I; KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase. | 0.974 |
Namu_1877 | eno | Namu_1877 | Namu_4431 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.527 |
Namu_1877 | mdh | Namu_1877 | Namu_2256 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.958 |
Namu_1877 | pckG | Namu_1877 | Namu_5314 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.973 |
Namu_1877 | ppc | Namu_1877 | Namu_4447 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.972 |
Namu_2341 | Namu_1766 | Namu_2341 | Namu_1766 | PFAM: Lactate/malate dehydrogenase; KEGG: mpt:Mpe_B0497 malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. | KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.591 |