STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_2261KEGG: bpd:BURPS668_2475 malate synthase; Belongs to the malate synthase family. (528 aa)    
Predicted Functional Partners:
Sros_3449
KEGG: sml:Smlt0232 putative isocitrate lyase.
 
 0.999
Sros_7971
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.989
Sros_1005
KEGG: mlo:mll3842 citrate synthase 2; Belongs to the citrate synthase family.
  
 0.961
Sros_1252
KEGG: aca:ACP_1789 citrate synthase 2; Belongs to the citrate synthase family.
  
 0.961
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.955
Sros_2258
KEGG: ade:Adeh_2865 hypothetical protein.
  
 
 0.954
Sros_2259
KEGG: ade:Adeh_2866 FAD linked oxidase-like.
  
 
 0.953
Sros_2260
KEGG: afw:Anae109_2921 D-lactate dehydrogenase (cytochrome).
  
 
 0.951
Sros_8500
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.946
Sros_8290
KEGG: ccs:CCNA_02045 acetyl-coenzyme A synthetase.
   
 
 0.936
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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