STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_8995KEGG: bsu:BSU24080 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (367 aa)    
Predicted Functional Partners:
Sros_2949
KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
  
 
 0.994
Sros_6420
KEGG: hch:HCH_06123 2-oxoisovalerate dehydrogenase.
  
 
 0.982
Sros_6148
KEGG: sde:Sde_3057 branched chain amino acid aminotransferase.
 
 
 0.925
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.916
Sros_8041
KEGG: nar:Saro_2671 branched-chain amino acid aminotransferase.
  
 
 0.916
cobB-2
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
 0.775
Sros_1254
KEGG: oca:OCAR_5440 isocitrate dehydrogenase, NADP- dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.741
Sros_5380
KEGG: aba:Acid345_0466 carbamoyl-phosphate synthase L chain, ATP-binding.
  
  
 0.632
Sros_8996
Hypothetical protein.
       0.626
Sros_8284
KEGG: sus:Acid_5307 alpha-ketoglutarate decarboxylase.
  
 
 0.617
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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