STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_5410PFAM: NUDIX hydrolase; KEGG: sma:SAV_6505 ADP-ribose pyrophosphatase. (208 aa)    
Predicted Functional Partners:
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.962
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.914
Caci_5884
PFAM: ribonuclease II; KEGG: nca:Noca_2017 ribonuclease II.
   
 0.660
Caci_5409
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: stp:Strop_0720 HAD family hydrolase.
  
  
 0.603
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.601
xerD
Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
  
 0.526
Caci_4760
PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: stp:Strop_2347 phage integrase family protein; Belongs to the 'phage' integrase family.
  
  
 0.526
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.513
Caci_1681
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: sco:SCO4096 ATP-dependent RNA helicase.
  
 0.513
Caci_2700
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: sco:SCO5920 DEAD-box RNA helicase.
  
 0.513
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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