STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_0215TIGRFAM: lysine biosynthesis enzyme LysX; alpha-L- glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: cau:Caur_0334 lysine biosynthesis enzyme LysX; Belongs to the RimK family. (298 aa)    
Predicted Functional Partners:
lysZ
Acetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
  
 0.983
Sthe_0213
PFAM: RimK domain protein ATP-grasp; KEGG: sgr:SGR_3478 putative lysine biosynthesis enzyme LysX.
 
  
 
0.966
lysK
N-acetyl-ornithine/N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
 
    0.945
Sthe_0212
TIGRFAM: lysine biosynthesis protein LysW; KEGG: ttj:TTHA1908 hypothetical protein.
 
   
 0.916
Sthe_2943
TIGRFAM: lysine biosynthesis enzyme LysX; alpha-L- glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: afw:Anae109_2113 alpha-L-glutamate ligase; Belongs to the RimK family.
  
  
 
0.906
Sthe_0315
PFAM: aminotransferase class I and II; KEGG: lch:Lcho_3539 GntR family transcriptional regulator.
     
  0.900
Sthe_2225
Transcriptional regulator, GntR family with aminotransferase domain protein; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sth:STH2754 class I aminotransferase protein.
     
  0.900
Sthe_3286
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: reh:H16_A2662 transcriptional regulator, MocR family.
     
  0.900
lysY
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
  
 0.839
lysJ
Acetylornithine and succinylornithine aminotransferase; Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
 
   
 0.448
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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