STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_0968TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short- chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: mth:MTH1789 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (345 aa)    
Predicted Functional Partners:
Sthe_2291
PFAM: Nucleotidyl transferase; KEGG: rci:RCIX198 glucose-1-phosphate thymidylyltransferase.
 
 0.999
Sthe_0980
KEGG: rci:RCIX202 dTDP-4-dehydrorhamnose 3,5 epimerase.
 
 
 0.998
Sthe_1659
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 0.997
Sthe_1687
PFAM: Nucleotidyl transferase; KEGG: hau:Haur_1221 nucleotidyl transferase.
 
  
 0.860
Sthe_1193
KEGG: cau:Caur_2850 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase.
 
  
 0.839
Sthe_1134
Nucleotide sugar dehydrogenase; KEGG: pen:PSEEN3453 GDP-mannose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase.
 
  
 0.825
Sthe_0662
PFAM: glycosyl transferase family 2; KEGG: rrs:RoseRS_4605 glycosyl transferase family protein.
 
  
 0.819
Sthe_3490
PFAM: UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: mes:Meso_2782 UDP-glucose/GDP-mannose dehydrogenase.
 
  
 0.819
Sthe_0724
PFAM: CBS domain containing protein; peptidase M50; SMART: CBS domain containing protein; KEGG: det:DET0769 protease family protein; Belongs to the peptidase M50B family.
  
  
 0.803
Sthe_0969
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: cau:Caur_1766 stage II sporulation E family protein.
       0.777
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
Server load: low (28%) [HD]