node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sthe_1124 | Sthe_1150 | Sthe_1124 | Sthe_1150 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | 0.926 |
Sthe_1124 | Sthe_1303 | Sthe_1124 | Sthe_1303 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | PFAM: Formiminotransferase-cyclodeaminase; KEGG: cau:Caur_3280 formiminotransferase- cyclodeaminase. | 0.909 |
Sthe_1124 | Sthe_2646 | Sthe_1124 | Sthe_2646 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); KEGG: afw:Anae109_3095 tRNA synthetase class I (M). | 0.908 |
Sthe_1124 | def | Sthe_1124 | Sthe_0382 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.647 |
Sthe_1124 | fmt | Sthe_1124 | Sthe_1176 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.923 |
Sthe_1124 | folD | Sthe_1124 | Sthe_1304 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.968 |
Sthe_1124 | gcvT | Sthe_1124 | Sthe_1287 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.907 |
Sthe_1124 | glyA | Sthe_1124 | Sthe_1283 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
Sthe_1124 | metG | Sthe_1124 | Sthe_2647 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.908 |
Sthe_1124 | purN | Sthe_1124 | Sthe_1363 | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.916 |
Sthe_1150 | Sthe_1124 | Sthe_1150 | Sthe_1124 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | PFAM: formyl transferase domain protein; KEGG: cau:Caur_2005 formyl transferase domain- containing protein. | 0.926 |
Sthe_1150 | Sthe_1303 | Sthe_1150 | Sthe_1303 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | PFAM: Formiminotransferase-cyclodeaminase; KEGG: cau:Caur_3280 formiminotransferase- cyclodeaminase. | 0.909 |
Sthe_1150 | Sthe_2646 | Sthe_1150 | Sthe_2646 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); KEGG: afw:Anae109_3095 tRNA synthetase class I (M). | 0.908 |
Sthe_1150 | def | Sthe_1150 | Sthe_0382 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.600 |
Sthe_1150 | fmt | Sthe_1150 | Sthe_1176 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.925 |
Sthe_1150 | folD | Sthe_1150 | Sthe_1304 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.963 |
Sthe_1150 | gcvT | Sthe_1150 | Sthe_1287 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.907 |
Sthe_1150 | glyA | Sthe_1150 | Sthe_1283 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
Sthe_1150 | metG | Sthe_1150 | Sthe_2647 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.908 |
Sthe_1150 | purN | Sthe_1150 | Sthe_1363 | PFAM: formyl transferase domain protein; KEGG: plu:plu1413 hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.916 |