node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Kfla_0413 | katG | Kfla_0413 | Kfla_2431 | PFAM: Catalase domain protein; KEGG: mpo:Mpop_3405 catalase; Belongs to the catalase family. | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.944 |
Kfla_0413 | kynU | Kfla_0413 | Kfla_5495 | PFAM: Catalase domain protein; KEGG: mpo:Mpop_3405 catalase; Belongs to the catalase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.905 |
Kfla_0413 | nbaC | Kfla_0413 | Kfla_5491 | PFAM: Catalase domain protein; KEGG: mpo:Mpop_3405 catalase; Belongs to the catalase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.900 |
Kfla_4324 | kynA | Kfla_4324 | Kfla_1675 | KEGG: rle:pRL80036 hypothetical protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.790 |
Kfla_4324 | kynU | Kfla_4324 | Kfla_5495 | KEGG: rle:pRL80036 hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.862 |
Kfla_5489 | Kfla_5490 | Kfla_5489 | Kfla_5490 | KEGG: mxa:MXAN_0913 hypothetical protein. | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | 0.780 |
Kfla_5489 | Kfla_5493 | Kfla_5489 | Kfla_5493 | KEGG: mxa:MXAN_0913 hypothetical protein. | TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_5132 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.511 |
Kfla_5489 | glgC | Kfla_5489 | Kfla_5496 | KEGG: mxa:MXAN_0913 hypothetical protein. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.506 |
Kfla_5489 | kmo | Kfla_5489 | Kfla_5494 | KEGG: mxa:MXAN_0913 hypothetical protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.516 |
Kfla_5489 | kynA | Kfla_5489 | Kfla_1675 | KEGG: mxa:MXAN_0913 hypothetical protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.424 |
Kfla_5489 | kynU | Kfla_5489 | Kfla_5495 | KEGG: mxa:MXAN_0913 hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.786 |
Kfla_5489 | nbaC | Kfla_5489 | Kfla_5491 | KEGG: mxa:MXAN_0913 hypothetical protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.780 |
Kfla_5490 | Kfla_5489 | Kfla_5490 | Kfla_5489 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | KEGG: mxa:MXAN_0913 hypothetical protein. | 0.780 |
Kfla_5490 | Kfla_5493 | Kfla_5490 | Kfla_5493 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_5132 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.977 |
Kfla_5490 | glgC | Kfla_5490 | Kfla_5496 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.506 |
Kfla_5490 | kmo | Kfla_5490 | Kfla_5494 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.897 |
Kfla_5490 | kynA | Kfla_5490 | Kfla_1675 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.774 |
Kfla_5490 | kynU | Kfla_5490 | Kfla_5495 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.910 |
Kfla_5490 | nbaC | Kfla_5490 | Kfla_5491 | PFAM: amidohydrolase 2; KEGG: swd:Swoo_1407 aminocarboxymuconate- semialdehyde decarboxylase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.995 |
Kfla_5493 | Kfla_5489 | Kfla_5493 | Kfla_5489 | TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_5132 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | KEGG: mxa:MXAN_0913 hypothetical protein. | 0.511 |