node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Minf_1213 | fabH | Minf_1213 | Minf_1216 | Predicted metal-binding, possibly nucleic acid-binding protein. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.729 |
Minf_1213 | hit-2 | Minf_1213 | Minf_1211 | Predicted metal-binding, possibly nucleic acid-binding protein. | HIT family hydrolase. | 0.587 |
Minf_1213 | nrdR | Minf_1213 | Minf_1212 | Predicted metal-binding, possibly nucleic acid-binding protein. | Predicted transcriptional regulato, contains Zn-ribbon and ATP-cone domains; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.575 |
Minf_1213 | plsX | Minf_1213 | Minf_1215 | Predicted metal-binding, possibly nucleic acid-binding protein. | Fatty acid/phospholipid biosynthesis enzyme; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.791 |
Minf_1213 | ribA | Minf_1213 | Minf_2430 | Predicted metal-binding, possibly nucleic acid-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.441 |
Minf_1213 | rpmF | Minf_1213 | Minf_1214 | Predicted metal-binding, possibly nucleic acid-binding protein. | Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.964 |
fabH | Minf_1213 | Minf_1216 | Minf_1213 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | Predicted metal-binding, possibly nucleic acid-binding protein. | 0.729 |
fabH | hit-2 | Minf_1216 | Minf_1211 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | HIT family hydrolase. | 0.473 |
fabH | nrdR | Minf_1216 | Minf_1212 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | Predicted transcriptional regulato, contains Zn-ribbon and ATP-cone domains; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.424 |
fabH | plsX | Minf_1216 | Minf_1215 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | Fatty acid/phospholipid biosynthesis enzyme; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.969 |
fabH | ribA | Minf_1216 | Minf_2430 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.519 |
fabH | rpmF | Minf_1216 | Minf_1214 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.824 |
hit-2 | Minf_1213 | Minf_1211 | Minf_1213 | HIT family hydrolase. | Predicted metal-binding, possibly nucleic acid-binding protein. | 0.587 |
hit-2 | fabH | Minf_1211 | Minf_1216 | HIT family hydrolase. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.473 |
hit-2 | nrdR | Minf_1211 | Minf_1212 | HIT family hydrolase. | Predicted transcriptional regulato, contains Zn-ribbon and ATP-cone domains; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.803 |
hit-2 | plsX | Minf_1211 | Minf_1215 | HIT family hydrolase. | Fatty acid/phospholipid biosynthesis enzyme; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.431 |
hit-2 | rpmF | Minf_1211 | Minf_1214 | HIT family hydrolase. | Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.453 |
nadE | nrdR | Minf_0725 | Minf_1212 | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Predicted transcriptional regulato, contains Zn-ribbon and ATP-cone domains; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.444 |
nadE | ribA | Minf_0725 | Minf_2430 | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.604 |
nadE | ribD | Minf_0725 | Minf_1660 | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Pyrimidine deaminase and pyrimidine reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.649 |