STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACX62971.1PFAM: ATP dependent DNA ligase; KEGG: pjd:Pjdr2_1127 ATP dependent DNA ligase. (288 aa)    
Predicted Functional Partners:
ACX67526.1
TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: pjd:Pjdr2_4985 DNA polymerase LigD, polymerase domain protein.
   
 0.981
ACX62312.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.927
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.921
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.846
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.774
ACX67221.1
Exodeoxyribonuclease III Xth; KEGG: bbe:BBR47_03090 exodeoxyribonuclease; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.667
ACX66734.1
TIGRFAM: histidinol-phosphate phosphatase family protein; HAD-superfamily hydrolase, subfamily IA, variant 1; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pjd:Pjdr2_4049 histidinol-phosphate phosphatase family protein.
   
 0.550
ACX64036.1
PFAM: SMC domain protein; KEGG: gtn:GTNG_0591 YirY.
   
 0.542
ACX67322.1
PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: pjd:Pjdr2_1409 5'-3' exonuclease.
  
 0.516
ACX65435.1
PFAM: Protein of unknown function DUF2277; KEGG: bbe:BBR47_46870 hypothetical protein.
  
     0.419
Your Current Organism:
Paenibacillus sp. Y412MC10
NCBI taxonomy Id: 481743
Other names: P. sp. Y412MC10
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