STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (305 aa)    
Predicted Functional Partners:
ACX67317.1
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: pjd:Pjdr2_4798 cystathionine gamma-synthase.
 
 
 0.992
ACX64225.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: pjd:Pjdr2_3767 homocysteine S-methyltransferase.
  
  
 0.972
ACX65369.1
KEGG: cth:Cthe_1842 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase.
 
 
 0.969
ACX67794.1
KEGG: pjd:Pjdr2_2192 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase.
 
 
 0.968
ACX63834.1
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: pjd:Pjdr2_4407 homoserine dehydrogenase.
  
 
 0.946
ACX67316.1
Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: pjd:Pjdr2_4797 cystathionine gamma-lyase.
 
  
 0.912
ACX65679.1
PFAM: alpha/beta hydrolase fold; KEGG: pjd:Pjdr2_1474 alpha/beta hydrolase fold protein; Belongs to the AB hydrolase superfamily. MetX family.
     
  0.900
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.835
ACX64650.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.821
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.818
Your Current Organism:
Paenibacillus sp. Y412MC10
NCBI taxonomy Id: 481743
Other names: P. sp. Y412MC10
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