node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJE38325.1 | KJE41498.1 | SG35_26335 | SG35_11065 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.846 |
KJE38325.1 | KJE42180.1 | SG35_26335 | SG35_08170 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
KJE38325.1 | KJE42181.1 | SG35_26335 | SG35_08175 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.987 |
KJE38325.1 | KJE42324.1 | SG35_26335 | SG35_06765 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.604 |
KJE38325.1 | KJE43952.1 | SG35_26335 | SG35_01045 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.731 |
KJE38325.1 | KJE43953.1 | SG35_26335 | SG35_01050 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-erythro-7,8-dihydroneopterin triphosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
KJE38325.1 | folE | SG35_26335 | SG35_01060 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |
KJE38325.1 | folP | SG35_26335 | SG35_06305 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
KJE38325.1 | pabB | SG35_26335 | SG35_17070 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Para-aminobenzoate synthase component 1; catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
KJE41498.1 | KJE38325.1 | SG35_11065 | SG35_26335 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |
KJE41498.1 | KJE42180.1 | SG35_11065 | SG35_08170 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
KJE41498.1 | KJE42181.1 | SG35_11065 | SG35_08175 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.844 |
KJE41498.1 | KJE43952.1 | SG35_11065 | SG35_01045 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
KJE41498.1 | KJE43953.1 | SG35_11065 | SG35_01050 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | D-erythro-7,8-dihydroneopterin triphosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.831 |
KJE41498.1 | folE | SG35_11065 | SG35_01060 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
KJE41498.1 | folP | SG35_11065 | SG35_06305 | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
KJE42180.1 | KJE38325.1 | SG35_08170 | SG35_26335 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
KJE42180.1 | KJE41498.1 | SG35_08170 | SG35_11065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | folC bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.801 |
KJE42180.1 | KJE42181.1 | SG35_08170 | SG35_08175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.995 |
KJE42180.1 | KJE42324.1 | SG35_08170 | SG35_06765 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.649 |