node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dret_0091 | Dret_0515 | Dret_0091 | Dret_0515 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | 0.955 |
Dret_0091 | Dret_0818 | Dret_0091 | Dret_0818 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | PFAM: AMP-dependent synthetase and ligase; KEGG: dvm:DvMF_0003 AMP-dependent synthetase and ligase. | 0.919 |
Dret_0091 | Dret_1035 | Dret_0091 | Dret_1035 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.928 |
Dret_0091 | Dret_1036 | Dret_0091 | Dret_1036 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.999 |
Dret_0091 | Dret_1121 | Dret_0091 | Dret_1121 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase. | 0.900 |
Dret_0091 | Dret_1706 | Dret_0091 | Dret_1706 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: dma:DMR_17880 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.905 |
Dret_0091 | acsA | Dret_0091 | Dret_2132 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.907 |
Dret_0091 | glcB | Dret_0091 | Dret_0331 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.900 |
Dret_0091 | leuA | Dret_0091 | Dret_1459 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.905 |
Dret_0515 | Dret_0091 | Dret_0515 | Dret_0091 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | 0.955 |
Dret_0515 | Dret_0818 | Dret_0515 | Dret_0818 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | PFAM: AMP-dependent synthetase and ligase; KEGG: dvm:DvMF_0003 AMP-dependent synthetase and ligase. | 0.921 |
Dret_0515 | Dret_1035 | Dret_0515 | Dret_1035 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.954 |
Dret_0515 | Dret_1036 | Dret_0515 | Dret_1036 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.999 |
Dret_0515 | Dret_1121 | Dret_0515 | Dret_1121 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase. | 0.900 |
Dret_0515 | Dret_1706 | Dret_0515 | Dret_1706 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: dma:DMR_17880 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.915 |
Dret_0515 | ackA | Dret_0515 | Dret_1034 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.512 |
Dret_0515 | acsA | Dret_0515 | Dret_2132 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.921 |
Dret_0515 | glcB | Dret_0515 | Dret_0331 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.900 |
Dret_0515 | leuA | Dret_0515 | Dret_1459 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.915 |
Dret_0818 | Dret_0091 | Dret_0818 | Dret_0091 | PFAM: AMP-dependent synthetase and ligase; KEGG: dvm:DvMF_0003 AMP-dependent synthetase and ligase. | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dma:DMR_07380 ketoisovalerate oxidoreductase subunit VorB. | 0.919 |