node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtox_0905 | Dtox_3758 | Dtox_0905 | Dtox_3758 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | 0.716 |
Dtox_0905 | leuB | Dtox_0905 | Dtox_0597 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.807 |
Dtox_0905 | proA | Dtox_0905 | Dtox_2013 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.694 |
Dtox_0905 | proB | Dtox_0905 | Dtox_3311 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.579 |
Dtox_0905 | proC | Dtox_0905 | Dtox_1084 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.621 |
Dtox_0905 | ribBA | Dtox_0905 | Dtox_2298 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.659 |
Dtox_0905 | rpmA | Dtox_0905 | Dtox_3314 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; KEGG: bha:BH3009 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.542 |
Dtox_3758 | Dtox_0905 | Dtox_3758 | Dtox_0905 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | 0.716 |
Dtox_3758 | leuB | Dtox_3758 | Dtox_0597 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.840 |
Dtox_3758 | proA | Dtox_3758 | Dtox_2013 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.902 |
Dtox_3758 | proB | Dtox_3758 | Dtox_3311 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.579 |
Dtox_3758 | proC | Dtox_3758 | Dtox_1084 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.679 |
Dtox_3758 | prs | Dtox_3758 | Dtox_0206 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.429 |
leuB | Dtox_0905 | Dtox_0597 | Dtox_0905 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: afw:Anae109_2039 prephenate dehydratase. | 0.807 |
leuB | Dtox_3758 | Dtox_0597 | Dtox_3758 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit). | 0.840 |
leuB | proA | Dtox_0597 | Dtox_2013 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.641 |
leuB | proB | Dtox_0597 | Dtox_3311 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.695 |
leuB | proC | Dtox_0597 | Dtox_1084 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.664 |
leuB | prs | Dtox_0597 | Dtox_0206 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.419 |
leuB | ribBA | Dtox_0597 | Dtox_2298 | 3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.453 |