STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phep_3623RNA methyltransferase, TrmA family; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (481 aa)    
Predicted Functional Partners:
Phep_3622
Hypothetical protein.
       0.851
Phep_3624
Hypothetical protein.
       0.567
Phep_1268
tRNA/rRNA methyltransferase (SpoU); PFAM: RNA 2'-O ribose methyltransferase substrate binding; SpoU rRNA Methylase family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.550
Phep_3211
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.542
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.532
Phep_3621
Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase.
  
    0.531
Phep_0995
Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.487
pheS
phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
    0.462
Phep_1569
PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase.
 
   
 0.461
Phep_1176
PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
    0.453
Your Current Organism:
Pedobacter heparinus
NCBI taxonomy Id: 485917
Other names: P. heparinus DSM 2366, Pedobacter heparinus DSM 2366, Pedobacter heparinus IFO 12017, Pedobacter heparinus LMG 10339, Pedobacter heparinus str. DSM 2366, Pedobacter heparinus strain DSM 2366
Server load: low (26%) [HD]