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hepC protein (Pedobacter heparinus) - STRING interaction network
"hepC" - Heparin-sulfate lyase in Pedobacter heparinus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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hepCHeparin-sulfate lyase; Specifically cleaves heparan sulfate-rich regions of acidic polysaccharides. Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Functions in cleaving metazoan heparan sulfate and providing carbon, nitrogen and sulfate sources for microorganisms; Belongs to the polysaccharide lyase 12 family (670 aa)    
Predicted Functional Partners:
Phep_2833
annotation not available (893 aa)
 
          0.792
Phep_2838
PFAM- Polysaccharide lyase family 8, super-sandwich domain; Lyase, N terminal; Lyase, catalytic (1077 aa)
 
          0.755
Phep_0784
Chondroitin sulfate ABC lyase; Broad-specificity glycosaminoglycan lyase (1030 aa)
 
          0.731
Phep_2840
PFAM- Polysaccharide lyase family 8, super-sandwich domain (989 aa)
 
          0.716
Phep_2843
RagB/SusD domain protein; PFAM- RagB, SusD and hypothetical proteins (622 aa)
 
          0.679
cslA
Chondroitinase-AC; PFAM- Polysaccharide lyase family 8, super-sandwich domain; Polysaccharide lyase family 8, C-terminal beta-sandwich domain; Polysaccharide lyase family 8, N terminal alpha-helical domain (700 aa)
 
          0.671
hepB
Heparin and heparin-sulfate lyase; Cleaves both heparin and heparan sulfate glycosaminoglycans through a beta-elimination mechanism. Cleaves heparin at alpha-D-GlcNp2S6S(1->4) alpha-L-IdoAp2S and heparan sulfate at alpha-D-GlcNp2Ac(or 2S)6OH(1->4)beta-D-GlcAp (772 aa)
   
          0.653
Phep_1840
annotation not available (538 aa)
   
          0.646
Phep_2828
RagB/SusD domain protein; PFAM- RagB, SusD and hypothetical proteins (549 aa)
 
          0.645
Phep_3594
annotation not available (307 aa)
   
          0.645
Your Current Organism:
Pedobacter heparinus
NCBI taxonomy Id: 485917
Other names: P. heparinus DSM 2366, Pedobacter heparinus, Pedobacter heparinus DSM 2366, Pedobacter heparinus DSM2366, Pedobacter heparinus IFO 12017, Pedobacter heparinus LMG 10339, Pedobacter heparinus str. DSM 2366, Pedobacter heparinus strain DSM 2366
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