STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKAR_LACBSVery-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa)    
Predicted Functional Partners:
B0DGH9_LACBS
Predicted protein.
   
 0.963
B0DP49_LACBS
Predicted protein.
  
 0.935
B0CRL2_LACBS
Delta 9-fatty acid desaturase protein; Belongs to the fatty acid desaturase type 1 family.
  
 0.925
B0D6J4_LACBS
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
  
 0.922
B0DLL9_LACBS
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
  
 0.922
B0DPU8_LACBS
Predicted protein.
   
 0.917
FAD12-5
Delta-12 fatty acid desaturase protein.
     
  0.900
B0CPI6_LACBS
Predicted protein.
   
 0.805
B0DGI3_LACBS
Predicted protein.
   
 
 0.647
B0DA13_LACBS
Signal peptidase subunit 3.
   
  
 0.557
Your Current Organism:
Laccaria bicolor
NCBI taxonomy Id: 486041
Other names: L. bicolor S238N-H82, Laccaria bicolor S238N-H82
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.