STRINGSTRING
pta1 protein (Schizosaccharomyces pombe) - STRING interaction network
"pta1" - mRNA cleavage and polyadenylation specificity factor complex subunit Pta1 in Schizosaccharomyces pombe
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pta1mRNA cleavage and polyadenylation specificity factor complex subunit Pta1; Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3’-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB (670 aa)    
Predicted Functional Partners:
SPAC824.04
WD repeat protein (predicted) (341 aa)
       
  0.994
yth1
mRNA cleavage and polyadenylation specificity factor complex Yth1; Component of the cleavage factor I (CF I) involved in pre-mRNA 3’-end processing (170 aa)
       
  0.994
dis2
Serine/threonine protein phosphatase PP1; Essential role in cell cycle control. PP1 is perhaps required for exit from mitosis (327 aa)
       
  0.992
SPCC74.02c
mRNA cleavage and polyadenylation specificity factor complex associated protein; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3’-end formation. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3’-end formation (710 aa)
     
    0.976
ssu72
Phosphoric ester hydrolase Ssu72 (predicted); Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb1) (197 aa)
     
 
  0.959
ysh1
mRNA cleavage and polyadenylation specificity factor complex endoribonuclease subunit Ysh1; Component of the cleavage factor I (CF I) involved in pre-mRNA 3’-end processing (757 aa)
     
    0.957
pfs2
WD repeat protein Pfs2; Required for 3’-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (509 aa)
     
 
  0.956
ctf1
mRNA cleavage and polyadenylation specificity factor complex subunit Ctf1; Component of the cleavage factor I (CF I) involved in pre-mRNA 3’-end processing (363 aa)
     
 
  0.941
SPBP8B7.15c.1
Ubiquitin-protein ligase E3 RBBP6 family involved in mRNA cleavage (predicted) (482 aa)
         
  0.927
cft1
Cleavage factor one Cft1 (predicted); RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3’-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3’-end formation (By similarity) (1441 aa)
     
 
    0.922
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
Server load: low (9%) [HD]