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sgt2 protein (Schizosaccharomyces pombe) - STRING interaction network
"sgt2" - Small glutamine-rich tetratricopeptide repeat-containing protein 2 in Schizosaccharomyces pombe
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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sgt2Small glutamine-rich tetratricopeptide repeat-containing protein 2; Co-chaperone that binds to the molecular chaperone Hsp70 and regulates Hsp70 ATPase activity (317 aa)    
Predicted Functional Partners:
get4
Golgi to ER traffic protein 4; May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane (303 aa)
     
 
  0.943
hsp104
Heat shock protein 104; Required, in concert with Hsp40 and Hsp70 and small Hsps, for the dissociation, resolubilization and refolding of aggregates of damaged proteins after heat or other environmental stresses. Extracts proteins from aggregates by unfolding and threading them in an ATP-dependent process through the axial channel of the protein hexamer, after which they can be refolded by components of the Hsp70/Hsp40 chaperone system (By similarity) (905 aa)
     
 
  0.930
rhp23
UV excision repair protein rhp23; Involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA (368 aa)
     
 
  0.915
hsp90
Heat shock protein 90 homolog; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Interacts with the wee1 protein kinase; which req [...] (704 aa)
   
 
  0.903
cct6
T-complex protein 1 subunit zeta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) (535 aa)
     
 
  0.868
get3
ATPase get3; ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (329 aa)
     
 
  0.841
SPBP4H10.12.1
UPF0303 protein P4H10.12; Belongs to the UPF0303 family (179 aa)
       
 
  0.820
wis2
40 kDa peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase D subfamily (356 aa)
   
 
  0.808
pre8
Probable proteasome subunit alpha type-2; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family (245 aa)
     
 
  0.782
SPBPB2B2.11.1
Uncharacterized protein PB2B2.11; Nucleotide-sugar 4,6-dehydratase (predicted) (365 aa)
         
  0.771
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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