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upf3 protein (Schizosaccharomyces pombe) - STRING interaction network
"upf3" - Nonsense-mediated mRNA decay protein 3 in Schizosaccharomyces pombe
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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upf3Nonsense-mediated mRNA decay protein 3; Involved in nonsense-mediated decay of mRNAs containing premature stop codons (278 aa)    
Predicted Functional Partners:
upf2
Nonsense-mediated mRNA decay protein 2; Involved in nonsense-mediated decay of mRNAs containing premature stop codons. It interacts, via its C-terminus, with NAM7/UPF1. Could be involved in determining the efficiency of translational termination or reinitiation or factors involved in the initial assembly of an initiation- and termination-competent mRNP (1049 aa)
     
  0.999
upf1
ATP-dependent helicase upf1; Required for rapid turnover of mRNAs containing a premature translational termination codon (925 aa)
     
  0.999
SPAC1F5.10
ATP-dependent RNA helicase fal1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity); Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily (394 aa)
     
  0.999
mnh1
Mago-nashi homolog Mnh1 (predicted) (147 aa)
     
  0.998
SPAC23A1.09.1
RNA-binding protein (predicted) (121 aa)
     
  0.997
sup35
Eukaryotic peptide chain release factor GTP-binding subunit; Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides (662 aa)
     
  0.996
est1
Telomere elongation protein est1; Directly involved in telomere replication. Associates with telomerase and during its interaction with trt1, telomerase activity is promoted; Belongs to the EST1 family (490 aa)
     
 
  0.996
pabp
Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] (653 aa)
     
  0.985
cbc1
Nuclear cap-binding protein subunit 1; Component of the CBC complex, which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs (780 aa)
     
  0.981
sup45
Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (433 aa)
       
  0.977
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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