STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpp1Trehalose-phosphatase; Trehalose-6-phosphate phosphatase Tpp1; In the C-terminal section; belongs to the trehalose phosphatase family (817 aa)    
Predicted Functional Partners:
tps1
Alpha,alpha-trehalose-phosphate synthase (udp-forming); Appears to have a role in spore germination. In S.pombe it appears to have no role in the control of the initial steps of glycolysis
  
0.999
SPACUNK4.16c.1
Trehalose 6-phosphate synthase complex regulatory subunit; Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit; Alpha,alpha-trehalose-phosphate synthase (predicted)
  
0.992
SPAC22F8.05.1
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit; Alpha,alpha-trehalose-phosphate synthase (predicted)
  
0.991
ntp1
Alpha,alpha-trehalase Ntp1; Belongs to the glycosyl hydrolase 37 family
  
 0.983
hxk2
Hexokinase 2; Catalyzes the phosphorylation of hexose (six-carbon sugars) to hexose 6-phosphate . Phosphorylates D-glucose, D-fructose and D-mannose . Compared to hxk1, has a much higher affinity for D-glucose . Constitutes the initial enzyme of glycolysis by catalyzing the phosphorylation of glucose to D-glucose 6- phosphate (Probable)
   
 
 0.924
SPCC794.10
Probable UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways
   
 
 0.903
ish1
Lea domain protein; Has a role in maintaining cell viability during stationary phase induced by stress response. Activated by the spc1 MAPK pathway
   
    0.863
SPBC21C3.19.1
Putative sbds family protein rtc3; SDO1-like protein C21C3.19; May play a role in RNA metabolism
   
    0.854
pnc1
Putative nicotinamidase pnc1; Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway
   
    0.850
SPAC29E6.09.1
Uncharacterized protein C29E6.09; Schizosaccharomyces specific protein
      
 0.839
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, fission yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.