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zds1 protein (Schizosaccharomyces pombe) - STRING interaction network
"zds1" - Protein zds1 in Schizosaccharomyces pombe
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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zds1Protein zds1; Has a role in establishing cell polarity. Also required for maintenance of cell wall integrity, sexual differentiation, calcium tolerance and cell morphology. Involved in Ras-MAPK signaling pathway at cell cortex. Has a role in meiosis (938 aa)    
Predicted Functional Partners:
pab1
Protein phosphatase PP2A regulatory subunit B; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates (463 aa)
     
 
  0.987
paa1
Protein phosphatase PP2A regulatory subunit A; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates (By similarity) (590 aa)
     
 
  0.869
ppa2
Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit; Essential role in cell cycle control. PP2A may be involved in controlling the entry into mitosis, possibly acting as an inhibitor; Belongs to the PPP phosphatase family. PP-2A subfamily (322 aa)
     
 
  0.827
cdc25
M-phase inducer phosphatase; This protein functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity (596 aa)
       
 
  0.780
spo12
Mitosis-specific protein spo12; Has a role in controlling mitotic cell cycle progression at the G2/M transition phase (90 aa)
           
  0.772
cut1
Separin; Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the rad21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by securin/cut2 protein. It is also required for pointed nuclear formation (1828 aa)
           
  0.753
clp1
Tyrosine-protein phosphatase CDC14 homolog; Protein phosphatase which antagonizes mitotic cyclin- dependent kinase cdc2, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint. Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases. Allows damaged actomyosin rings to be maintaine [...] (537 aa)
     
   
  0.742
pre10
Probable proteasome subunit alpha type-7; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family (253 aa)
       
      0.724
ras1
Ras-like protein 1; Participates in the process of sexual differentiation and the determination of cell shape. Essential for mating and for recognition of the mating pheromone, but not for vegetative growth. Does not regulate the intracellular cAMP level. Regulates two downstream pathways, namely the byr2/byr1/spk1 mitogen- activated protein kinase cascade and the cdc42 small G protein pathway. The former is relevant to mating and sporulation, whereas the latter is relevant to mating, cell growth and cell morphology (219 aa)
       
 
  0.718
par2
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 2 isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Has a role in cell shape control and septum formation (627 aa)
     
 
  0.662
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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