Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fub2 | hus5 | SPBC16H5.03c.1 | SPAC30D11.13.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | 0.999 |
| fub2 | nse2 | SPBC16H5.03c.1 | SPAC16A10.06c.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Smc5-6 complex non-SMC subunit 2; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis | 0.958 |
| fub2 | pli1 | SPBC16H5.03c.1 | SPAC1687.05.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | E3 SUMO-protein ligase PIAS1; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Involved in the maintenance of the centromere and in telomere length. Regulates recombination, via extension sumoylation, particularly within the heterochromatin repeats | 0.976 |
| fub2 | pmt3 | SPBC16H5.03c.1 | SPBC365.06.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Small ubiquitin-like modifier pmt3; Required for chromosome segregation where it may be involved in microtubule assembly. Loss of smt3 leads to an increase in telomere length | 0.999 |
| fub2 | rad31 | SPBC16H5.03c.1 | SPAC4C5.04.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Ubiquitin-like 1-activating enzyme e1 a; Could be involved in a ubiquitin-related process important for DNA damage tolerance. Acts in a process which is defective in the checkpoint rad mutants and which involves hus5 | 0.999 |
| fub2 | rbx1 | SPBC16H5.03c.1 | SPAC23H4.18c.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Ring-box protein 1; Component of E3 ubiquitin ligase SCF complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recruit the E2 ubiquitination enzyme, like UBC3/CDC34, to the complex and brings it into close proximity to the substrate. Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional sile [...] | 0.758 |
| fub2 | ubc12 | SPBC16H5.03c.1 | SPCC777.10c.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Ubiquitin-conjugating enzyme e2 m; Accepts the ubiquitin-like protein NEDD8/RUB1 from the UBA3- ULA1 E1 complex and catalyzes its covalent attachment to other proteins | 0.938 |
| fub2 | ulp1 | SPBC16H5.03c.1 | SPBC19G7.09.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Sumo deconjugating enzyme ulp1; A cysteine protease that proteolytically removes the C- terminus of pmt3 | 0.925 |
| fub2 | ulp2 | SPBC16H5.03c.1 | SPAC17A5.07c.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Ubiquitin-like-specific protease 2; SUMO deconjugating cysteine peptidase Ulp2 (predicted) | 0.954 |
| fub2 | urm1 | SPBC16H5.03c.1 | SPCC548.04.1 | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | Putative ubiquitin family protein urm1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of [...] | 0.839 |
| hus5 | fub2 | SPAC30D11.13.1 | SPBC16H5.03c.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | 0.999 |
| hus5 | nse2 | SPAC30D11.13.1 | SPAC16A10.06c.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Smc5-6 complex non-SMC subunit 2; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis | 0.999 |
| hus5 | pli1 | SPAC30D11.13.1 | SPAC1687.05.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | E3 SUMO-protein ligase PIAS1; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Involved in the maintenance of the centromere and in telomere length. Regulates recombination, via extension sumoylation, particularly within the heterochromatin repeats | 0.999 |
| hus5 | pmt3 | SPAC30D11.13.1 | SPBC365.06.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Small ubiquitin-like modifier pmt3; Required for chromosome segregation where it may be involved in microtubule assembly. Loss of smt3 leads to an increase in telomere length | 0.999 |
| hus5 | rad31 | SPAC30D11.13.1 | SPAC4C5.04.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Ubiquitin-like 1-activating enzyme e1 a; Could be involved in a ubiquitin-related process important for DNA damage tolerance. Acts in a process which is defective in the checkpoint rad mutants and which involves hus5 | 0.999 |
| hus5 | rbx1 | SPAC30D11.13.1 | SPAC23H4.18c.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Ring-box protein 1; Component of E3 ubiquitin ligase SCF complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recruit the E2 ubiquitination enzyme, like UBC3/CDC34, to the complex and brings it into close proximity to the substrate. Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional sile [...] | 0.954 |
| hus5 | ulp1 | SPAC30D11.13.1 | SPBC19G7.09.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Sumo deconjugating enzyme ulp1; A cysteine protease that proteolytically removes the C- terminus of pmt3 | 0.965 |
| hus5 | ulp2 | SPAC30D11.13.1 | SPAC17A5.07c.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Ubiquitin-like-specific protease 2; SUMO deconjugating cysteine peptidase Ulp2 (predicted) | 0.978 |
| hus5 | urm1 | SPAC30D11.13.1 | SPCC548.04.1 | Small ubiquitin-like modifier-conjugating enzyme hus5; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process | Putative ubiquitin family protein urm1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of [...] | 0.484 |
| nse2 | fub2 | SPAC16A10.06c.1 | SPBC16H5.03c.1 | Smc5-6 complex non-SMC subunit 2; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis | Putative sumo e1-like activator enzyme fub2; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue on aos1 (By similarity) | 0.958 |
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