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spn4 protein (Schizosaccharomyces pombe) - STRING interaction network
"spn4" - Septin homolog spn4 in Schizosaccharomyces pombe
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
spn4Septin homolog spn4; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells (380 aa)    
Predicted Functional Partners:
spn2
Septin homolog spn2; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells. Involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4- phosphate (331 aa)
     
0.982
spn3
Septin homolog spn3; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells (412 aa)
     
0.977
spn1
Septin homolog spn1; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells (469 aa)
     
0.975
mid2
Septin ring organizing protein mid2; Responsible for the proper stability and function of septins during cytokinesis. Required for the correct formation of the medial septin ring structure in mitosis and for the proper localization of endo-glucanases agn1 and eng1, which are needed for efficient cell separation. May act as a landmark for the localization of hydrolytic proteins to the medial region (706 aa)
       
 
  0.935
mfs2
MFS family membrane transporter Mfs2 (predicted) (546 aa)
           
  0.830
agn1
Glucan endo-1,3-alpha-glucosidase agn1; Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur. Hydrolyzes 1,3-alpha- glucan predominantly into pentasaccharides (424 aa)
       
 
  0.814
pom2
Serine/threonine-protein kinase ppk5; Has a role in meiosis (836 aa)
     
 
  0.698
cdc42
Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily (192 aa)
       
 
  0.672
ppb1
Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape (554 aa)
     
 
  0.663
cdr2
Mitosis inducer protein kinase cdr2; Acts as a mitotic inducer. In G2 it negatively regulates wee1, a mitotic inhibitor. Also has a role in cytokinesis where it required for proper septum formation (775 aa)
       
 
  0.647
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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