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saf4 protein (Schizosaccharomyces pombe) - STRING interaction network
"saf4" - Protein saf4 in Schizosaccharomyces pombe
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
saf4Protein saf4; May be involved in mRNA splicing (299 aa)    
Predicted Functional Partners:
cdc5
Pre-mRNA-splicing factor cdc5; Involved in mRNA splicing and cell cycle control; Belongs to the CEF1 family (757 aa)
     
  0.999
cwf10
Pre-mRNA-splicing factor cwf10; Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily (984 aa)
       
  0.999
prp19
Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase involved in pre-mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. May also function in DNA repair; Belongs to the WD repeat PRP19 family (488 aa)
       
  0.997
prp17
Pre-mRNA-processing factor 17; Functions in the second step of pre-mRNA splicing. Involved in splicing intron which are longer than 200 nucleotides (558 aa)
     
  0.997
cwf14
Pre-mRNA-splicing factor cwf14; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome (146 aa)
     
  0.996
cwf2
Pre-mRNA-splicing factor cwf2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the "nineteen complex" NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre- mRNA intron near the 5’ splice site during the activation and catalyti [...] (388 aa)
       
  0.992
cwf3
Pre-mRNA-splicing factor cwf3; Involved in pre-mRNA splicing and cell cycle progression; Belongs to the crooked-neck family (790 aa)
     
  0.990
cwf4
Pre-mRNA-splicing factor cwf4; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity); Belongs to the crooked-neck family (674 aa)
     
  0.990
syf2
Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing (229 aa)
     
  0.988
prp45
Pre-mRNA-processing protein 45; Involved in pre-mRNA splicing; Belongs to the SNW family (557 aa)
     
  0.987
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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