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tom40 protein (Schizosaccharomyces pombe) - STRING interaction network
"tom40" - Probable mitochondrial import receptor subunit tom40 in Schizosaccharomyces pombe
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Predicted Interactions
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textmining
co-expression
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tom40Probable mitochondrial import receptor subunit tom40; Channel-forming protein essential for import of protein precursors into mitochondria (344 aa)    
Predicted Functional Partners:
tom20
Mitochondrial import receptor subunit tom20; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity) (152 aa)
     
  0.998
tom70
Probable mitochondrial import receptor subunit tom70; Receptor that accelerates the import of all mitochondrial precursor proteins (625 aa)
     
  0.996
tom22
Mitochondrial import receptor subunit tom22; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. Docks tom20 and tom70 for interaction with the general tom40 import pore (GIP) complex. May regulate the TOM machinery organization, stability and channel gating (By similarity) (144 aa)
     
  0.995
tim50
Mitochondrial import inner membrane translocase subunit tim50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity) (452 aa)
     
 
  0.993
mdm10
Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (370 aa)
       
  0.989
sam50
SAM50-like protein SPAC17C9.06; May be required for the assembly pathway of mitochondrial outer membrane proteins; Belongs to the SAM50/omp85 family (475 aa)
     
  0.988
tom7
Mitochondrial TOM complex subunit Tom7 (predicted); Belongs to the Tom7 family (49 aa)
     
  0.987
tim13
Mitochondrial import inner membrane translocase subunit tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates [...] (95 aa)
     
   
  0.980
tim23
Mitochondrial import inner membrane translocase subunit tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (210 aa)
     
 
  0.977
tim44
Mitochondrial import inner membrane translocase subunit tim44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 and its co- chaperone (mge1) to drive protein translocation into the matrix using ATP as an energy source (427 aa)
     
   
  0.972
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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