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syj1 protein (Schizosaccharomyces pombe) - STRING interaction network
"syj1" - Inositol-1,4,5-trisphosphate 5-phosphatase 1 in Schizosaccharomyces pombe
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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syj1Inositol-1,4,5-trisphosphate 5-phosphatase 1; Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Involved in distinct membrane trafficking and signal transduction pathways. Highly active against a range of soluble and lipid inositol phosphates. Active in dephosphorylating the 5-position of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 and to a lesser extent Ins(1,4,5,6)P4. The enzyme is also active against PI(4,5)P2 presented in sonicated vesicles and Triton mixed micelles, and somewhat less active against PI(3,5)P [...] (1076 aa)    
Predicted Functional Partners:
stt4
Phosphatidylinositol 4-kinase stt4; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate (1877 aa)
     
  0.950
its3
Phosphatidylinositol 4-phosphate 5-kinase its3; Involved, together with the calcineurin ppb1, in cytokinesis (742 aa)
     
  0.945
pik1
Phosphatidylinositol 4-kinase pik1; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate. PIK1 is part of a nuclear phosphoinositide cycle and could control cytokinesis through the actin cytoskeleton (By similarity); Belongs to the PI3/PI4-kinase family (851 aa)
     
  0.943
SPBC19F5.03.1
Uncharacterized protein C19F5.03; Inositol polyphosphate phosphatase (predicted) (598 aa)
     
0.931
SPAC3C7.01c.1
Uncharacterized protein C3C7.01c; Inositol polyphosphate phosphatase (predicted); To yeast RSD1 and S.pombe SpBC19F5.03 (611 aa)
     
0.930
plc1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (899 aa)
     
  0.927
lsb6
Phosphatidylinositol 4-kinase lsb6; May play a role in endocytic and/or exocytic pathways; Belongs to the PI3/PI4-kinase family (624 aa)
     
 
  0.922
ptn1
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1; Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels (348 aa)
     
  0.917
SPAC823.07
Protein PER1 homolog; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for efficient transport of GPI-anchor proteins (By similarity) (331 aa)
     
   
  0.872
syj2
Inositol-1,4,5-trisphosphate 5-phosphatase 2; Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Involved in distinct membrane trafficking and signal transduction pathways. Highly active against a range of soluble and lipid inositol phosphates. Active in dephosphorylating the 5-position of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 and to a lesser extent Ins(1,4,5,6)P4 (By similarity); In the central section; belongs to the inositol 1,4,5- trisphosphate 5-phosphatase family (889 aa)
         
0.831
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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