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srk1 protein (Schizosaccharomyces pombe) - STRING interaction network
"srk1" - Serine/threonine-protein kinase srk1 in Schizosaccharomyces pombe
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
srk1Serine/threonine-protein kinase srk1; Has a role in the regulation of meiosis via the sty1 stress-activated MAPK pathway. Inhibits nitrogen-limitation induced arrest at G1 (580 aa)    
Predicted Functional Partners:
cdc25
M-phase inducer phosphatase; This protein functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity (596 aa)
     
  0.967
cmk2
Calcium/calmodulin-dependent protein kinase type II; Has a role in the regulation of G2/M transition during mitosis (504 aa)
         
0.905
pyp2
Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2 (711 aa)
     
 
  0.880
SPBC660.05
WW domain containing conserved fungal protein (143 aa)
     
        0.853
rad24
DNA damage checkpoint protein rad24; Required for the DNA damage checkpoint that ensures that DNA damage is repaired before mitosis is attempted. Acts as a negative regulator of meiosis by antagonizing the function of mei2. It inhibits the association of meiRNA (a non-coding RNA molecule required for the nuclear mei2 dot formation) to the phosphorylated but not to the unphosphorylated form of mei2 in vitro (270 aa)
       
 
  0.852
SPCC191.01
Uncharacterized protein C191.01; Schizosaccharomyces specific protein (178 aa)
     
        0.841
cam1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (150 aa)
 
   
 
  0.823
sty1
Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell- cycle G2/M control with changes in the extracellular environment that [...] (349 aa)
       
 
0.800
sfk1
Protein sfk1; May control the production of phosphatidylinositol 4- phosphate (PI4P) (328 aa)
     
        0.798
SPAC2H10.01.1
Uncharacterized transcriptional regulatory protein C2H10.01; Transcription factor, zf-fungal binuclear cluster type (predicted) (480 aa)
     
   
  0.725
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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