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sif2 protein (Schizosaccharomyces pombe) - STRING interaction network
"sif2" - Sad1 interacting factor 2 in Schizosaccharomyces pombe
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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sif2Sad1 interacting factor 2 (predicted); Required for sporulation where it is believed to have a role in meiotic nuclear division (382 aa)    
Predicted Functional Partners:
mrps16
Mitochondrial ribosomal protein subunit S16 (predicted) (96 aa)
     
        0.705
hos2
Histone deacetylase (class I) Hos2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Is not essential (434 aa)
     
      0.612
ekc1
Protein phosphatase regulatory subunit Ekc1 (predicted); Has a role in chromosome segregation. May provide a dynamic connection between kinetochore microtubules and kinetochore chromatin (838 aa)
       
      0.600
sad1
Spindle pole body protein Sad1; Associates with the spindle pole body and maintains a functional interface between the nuclear membrane and the microtubule motor proteins. Involved in chromosome segregation during meiosis where it associates with the telomeres (514 aa)
     
      0.502
vps33
HOPS/CORVET complex subunit, vacuolar sorting protein Vps33; Essential for vacuolar biogenesis, maturation and function. Involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole (592 aa)
     
        0.461
pi053
Mitochondrial translational activator of cytochrome C oxidase I (predicted) (293 aa)
     
   
  0.458
rad4
BRCT domain protein Rad4; Essential component for DNA replication and also the checkpoint control system which couples S and M phases. May directly or indirectly interact with chromatin proteins to form the complex required for the initiation and/or progression of DNA synthesis (PubMed-8343962, PubMed-7957098). Interacts simultaneously with both ’Thr-187’ phosphorylation sites in a crb2 dimer for establishing the DNA checkpoint (PubMed-24074952) (648 aa)
     
   
  0.414
SPAC3G6.03c.1
Maf-like protein (241 aa)
           
  0.414
yih1
IMPACT homolog, translational regulator (predicted); Translational regulator that ensures constant high levels of translation under amino acid starvation. Plays a role as a negative regulator of the gcn2 kinase activity; impairs gcn1- mediated gcn2 activation, and hence gcn2-mediated eIF-2-alpha phosphorylation in amino acid-starved cells and subsequent down- regulation of protein synthesis. In normal conditions, it resides in a actin complex and has no activity (280 aa)
           
  0.414
rnh1
Ribonuclease H Rnh1 (predicted); Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (264 aa)
     
        0.410
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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