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SPCC320.03 protein (Schizosaccharomyces pombe) - STRING interaction network
"SPCC320.03" - Uncharacterized transcriptional regulatory protein C320.03 in Schizosaccharomyces pombe
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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SPCC320.03Uncharacterized transcriptional regulatory protein C320.03; Transcription factor (predicted) (867 aa)    
Predicted Functional Partners:
scr1
DNA-binding protein scr1; Involved in carbon catabolite repression. Represses the transcription of various genes including the inv1 gene (565 aa)
       
 
  0.890
ssn6
General transcriptional corepressor ssn6; Acts as component of the ssn6-tup corepressor complexes, which are involved in the repression of many genes in a wide variety of physiological processes. May also be involved in the derepression of at least some target genes. The complex is recruited to target genes by interaction with DNA-bound transcriptional repressors. The complex recruits histone deacetylases to produce a repressive chromatin structure, interacts with hypoacetylated N-terminal tails of histones H3 and H4 that have been programmed for repression by the action of histone dea [...] (1102 aa)
       
 
  0.851
pof2
SCF E3 ubiquitin ligase complex F-box protein pof2; Involved in substrate recognition in ubiquitin-dependent degradation (463 aa)
       
 
  0.849
hxk1
Hexokinase-1; Has low affinity for glucose and some of its analogs; Belongs to the hexokinase family (484 aa)
       
 
  0.730
laf1
SWIRM domain-containing protein laf1; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (297 aa)
           
  0.722
pmp3
Plasma membrane proteolipid 3; Plays a role in the regulation of membrane potential. Could mediate a proton leak. Regulated by the spc1-atf1 pathway and so expression is stress-induced (57 aa)
           
  0.721
ssp2
SNF1-like protein kinase ssp2; Serine/threonine protein kinase essential for release from glucose repression via the phosphorylation of scr1 upon glucose deprivation. Catalytic subunit of the AMP-activated protein kinase complex also known as the SNF1 kinase complex (Snf1c), a central regulator of cellular energy homeostasis, which, in response to a fall in intracellular ATP levels, activates energy-producing pathways and inhibits energy- consuming processes. The complex phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, leading to transcriptional activation t [...] (576 aa)
       
 
  0.707
SPBC530.11c.1
Uncharacterized transcriptional regulatory protein C530.11c; Transcription factor, zf-fungal binuclear cluster type (predicted) (819 aa)
           
  0.687
cbs2
5’-AMP-activated protein kinase subunit gamma; Adenine nucleotides-binding subunit gamma of AMP- activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes- inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators [...] (334 aa)
           
  0.602
SPAC959.01
Putative invertase; Beta-fructofuranosidase (predicted); Belongs to the glycosyl hydrolase 32 family (508 aa)
           
  0.582
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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